Structural Diversity, Fitness Cost, and Stability of a BlaNDM-1-Bearing Cointegrate Plasmid in Klebsiella pneumoniae and Escherichia coli
Cointegrate/hybrid plasmids combine the genetic elements of two or more Food Canisters plasmids and generally carry abundant antimicrobial resistance determinants.Hence, the spread of cointegrate plasmids will accelerate the transmission of AMR genes.To evaluate the transmission risk caused by cointegrate plasmids, we investigated the structural di